Perinatal complications and executive dysfunction in early-onset schizophrenia
نویسندگان
چکیده
منابع مشابه
Increased developmental deviance and premorbid dysfunction in early onset schizophrenia.
Abnormal neurodevelopment and poor premorbid function have been described in schizophrenia. It is unclear whether abnormalities in these domains are increased in patients with early onset schizophrenia (EOS; onset before the 18th birthday) and whether they act to precipitate the earlier onset of the disorder. To address these questions, we collected information based on maternal interviews abou...
متن کاملExecutive dysfunction in schizophrenia and its association with mentalizing abilities.
INTRODUCTION Patients with schizophrenia have been found impaired in important aspects of their basic and social cognition. Our aim in this study is to explore the relationship between executive function (EF) and theory of mind (ToM) deficiencies in patients that suffer the illness. MATERIALS AND METHODS Twenty-two Spanish-speaking inpatients and 22 healthy controls matched in age, sex, educa...
متن کاملPerinatal complications and schizophrenia: involvement of the immune system
The neurodevelopmental hypothesis of schizophrenia suggests that, at least in part, events occurring within the intrauterine or perinatal environment at critical times of brain development underlies emergence of the psychosis observed during adulthood, and brain pathologies that are hypothesized to be from birth. All potential risks stimulate activation of the immune system, and are suggested t...
متن کاملFamilial liability, obstetric complications and childhood development abnormalities in early onset schizophrenia: a case control study
BACKGROUND Genetic and environmental risk factors and gene-environment interactions are linked to higher likelihood of developing schizophrenia in accordance with the neurodevelopmental model of disease; little is known about risk factors and early development in early-onset schizophrenia (EOS) and very early-onset schizophrenia (VEOS). METHODS We present a case-control study of a sample of 2...
متن کاملPathophysiology of early onset schizophrenia.
Early onset schizophrenia (with onset before adulthood) represents a rarer and possibly more severe form of the disorder which has received particular attention in the last two decades. Current evidence strongly suggest continuity with adult onset schizophrenia, with phenomenological, cognitive, genetic and neuroimaging data pointing towards similar neurobiological correlates and clinical defic...
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ژورنال
عنوان ژورنال: BMC Psychiatry
سال: 2020
ISSN: 1471-244X
DOI: 10.1186/s12888-020-02517-z